Door onafhankelijke onderzoekers

Vertaling: Ed Gunneweg

• 1. Stegink, L.: Filer, L.J. Jr. Aspartame Physiology and Biochemistry.University of Iowa College of Medicine. Iowa City, IA Marcel Dekker,Inc. 1984.


• 2. Camfield, P.R.: Camfield, J.M.: Dooley, J.M.: et al with generalizedabsence epilepsy: A double-blind controlled study. Neurology (42) 1000-1003(May 1992)


• 3. Boehm, M.: Bada, J. Racemization of aspartic acid and phenylalaninein the sweetener aspartame at 100 degrees C. Proc. Natl. Acad. Sci. USA(81) August 1984.


• 4. Walton, R. G. "Seizure and mania after high intake of aspartame."Psychopathology 17:98-106 (1984)


• 5. Drake, M.E. "Panic Attacks and Excessive Aspartame Ingestion." TheLancet (Sept 13, l986) p. 631


• 6. Walton, R. G. "The Possible Role of Aspartame in Seizure Induction"Proceedings of the First International Meeting on Dietary Phenylalanineand Brain Function. (May 8-10 1987) pp.495-499


• 7. Epstein, C. M.: Trotter, J.F.: et al "EEG Mean Frequencies areSensitive indices of Phenylalanine Effects on Normal Brain."Electroencephalography and Clinical Neurophysiology 72:133-139 (1989)


• 8. Pinto, J.M.B." Maher, T. J. "Administration of Aspartame PotentiatesPentlyeneterazole and Fluorothyl-Induced Seizure in Mice."Neuropharmacology 27 (1):51-55 (l988)


• 9. Olney, John "Excitatory Neurotoxins as Food Additives: An Evaluationof Risk." Neurotoxicology 2:163-192 (1980)


• 10. Koehler S.M.: Glaros, A. "The effect of aspartame on migraineheadache." Headache 28:000-000 (l988)


• 11. Edmeada, J. Editorial: "Aspartame and Headache." Headache, pp.64-65(February, 1988)


• 12. Lipton, R. B.; Newman, L. C.: Solomon, S. "Aspartame and headache,(re:Schiffman et al study)," New England Journal of Medicine 318 (18):1200-1201 (May 5, 1988)


• 13. Steinmetzer, R.V.: Kunkel, R.S. "Aspartame and Headache" New EnglandJournal of Medicine 318 (18): 1201 (May 5, 1988)


• 14. Koehler, Shirley; and Glaros, Alan. "The Effect of Aspartame onMigraine Headache." Headache 28 (1):10-14 (l988)


• 15. Olney, J. W.; and Ho, Ol. "Brain damage in Infant Mice FollowingOral Intake of Glutamate, Aspartate or Cysteine." Nature 227:609-611(August 8, 1970)


• 16. Olney, J. W. "Excitotoxic Food Additives - Relevance of AnimalStudies to Human Safety." Neurological Behavioral Toxicology andTeratology 6:455-462 (l984).


• 17. Olney, J. W.; Labruyere, J: DeGubaret, T. "Brain Damage in Mice fromVoluntary Ingestion of Glutamate and Aspartame." NeurobehavioralToxicology 2:125-129 (l980)


• 18. Roberts, H. J. "Does Aspartame Cause Human Brain cancer?" Journal ofAdvances in Medicine 4 (4): 231-241 (Winter, 1991).


• 19. Potenza, D." El-Mailakh, Rif S. "Aspartame: Clinical Update."Connecticut Medical Journal 53 (7): 395-400 (l989)


• 20. Sardesai, V.M.: Holliday, J.F.; et al. "Effect of Aspartame in Normaland Diabetic Rats." Biochemical Archives 2:237-243 (l986)


• 21. Federal Register 48:54993-54995 (Dec 8, l983)


• 22. Yokigoshi, H.: Roberts, C. F&t;: Caballero, B.: Wurtman, R. J."Effects of Aspartame and Glucose Administration on Brain and PlasmaLevels of Large Neutral Amino Acids and Brain 5-Hydroxyindoles." AmericanJournal of Clinical Nutrition. 40:1-7 (July 1, 1984)


• 23. Krause, W.:Halminksi, M." et al. "Biochemical and NeuropsychologicalEffects of Elevated Plasma Phenylalanine in Patients with TreatedPhenylketonuria." Journal of Clinical Investigation 75: 40-48 (January,1985).


• 24. Pardridge, W.M. "Potential Effects of the Dipeptide SweetenerAspartame on the Brain. Nutrition and the Brain 7:199-241 (l986)


• 25. Gaines, S. M.: Bada, J.I. "Reversed Phase, High-Performance LiquidChromatographic Separation of Aspartame Diastereomeric DecompositionProducts." Journal of Chromatography. 389-:219-225 (l987)


• 26. Filer, L. J.; Stegnink. L.D. "Effect of Aspartame on PlasmaPhenylalanine Concentration in Humans." Proceedings of the FirstInternational Meeting on Dietary Phenylalanine and the Brain Function(May 8-10, l987) pp 25-26


• 27. Matalon, R.: Michals, K.:et al. "Aspartame Consumption in NormalIndividuals and Carriers for Phenylketonuria (PKU)." Proceedings of theFirst International Meeting on Dietary Phenylalanine and Brain Function(May 8-10, l987) pp. 81-93


• 28. Matalon, R. Michals, K." Sullivan, D.; et al. "Aspartame Consumptionin Normal Individuals and Carriers for Phenylketonuria (PKU)." Universityof Illinois at Chicago, Department of Pediatrics, Nutrition and MedicalDietetics and Epidemiology and Biometry, Chicago, Illinois (l986).


• 29. Tocci, P.M.: Beber, B. "Anomalous Phenylalanine Loading Responses inRelation to Cleft Lip and Cleft Palate." Pediatrics 52: 109-113 (July l973)


• 30. Steilman, S.D.:Garfinkel, L. "Artificial Sweetener and One YearWeight Change Among Women." Preventative Medicine 15:195-202 (l986)


• 31. Blundell, J.E.: Hill, A.H. "Paradoxical Effects of an IntenseSweetener (Aspartame) on Appetite." The Lancet (May 10, l986) pp. l092-1093.


• 32. Garriga, M., MD; and Metcalf, D.,MD. "Aspartame intolerance" Annalsof Allergy 61:63-66 (December 1988)


• 33. United States General Accounting Office/HRD-87-86, Food and DrugAdministration's Approval of Aspartame. (June l987)


• 34. Council Report: Aspartame review of safety issues. Journal of theAmerican Medical Association l985:254 (3):400


• 35. Johns,D.R., MD, Letter to the Editor. The New England Journal ofMedicine (August 14, 1986)


• 36. Novick, N.J. "Aspartame-induced granulomatous panniculitis." Annalsof Internal Medicine 102:206-207 (l985)


• 37. McCauliffe, D.: and Poitras, K. "Aspartame-induced lobularpanniculitis." J of the American Academy of Dermatology 24 (2):298-299(February 1991)


• 38. Kulezycki,A.Jr. "Aspartame induced urticaria. Annals of InternalMedicine 104:207-208 (l986)


• 39. Wurtman, R.J. "Aspartame: possible effect on seizuresusceptibility." Lancet 2:1060. (l985)


• 40. Schainker, N. and Olney, J.W. "Glutamate Type Hypothalamic PituitarySyndrome in Mice Treated with Aspartame or Cysteate in Infancy." Journalof Neutral Trans. 35: 207-215 (l974)


• 41. Reynolds, W. A.: Butler, V." Lemley-Johnson, N. "HypothalamicMorphology Following ingestion of Aspartame of MSG in the Neonatal Rodentand Primate: A Preliminary Report" Journal of Toxicology andEnvironmental Health 2:471-480 (l976)


• 42. Pizzi, W.J.:Tabor, J.M.:Barnhart,J. "Somatic, Behavioral andReproductive Disturbances in Mice Following Neonatal Administration ofSodium L-Aspartate." Pharmacological Biochemical Behavior 9::481-485 (l976)


• 43. Stegnik, L.D.: Brummel, M.C.; et al, "Blood Methanol Concentrationsin Normal Adult Subjects Administered Abuse dose of Aspartame." J ofToxicological Environmental Health 7:281-290 (l981)


• 44. Monte, Woodrow, "Aspartame: Methanol and the Public Health," Journalof Applied Nutrition 36(1):42-54 (l984).


• 45. Bergeron, R.:Cardinal, J." et al. "Prevention of Methanol Toxicityby Ethanol Therapy." New England Journal of Medicine (December 9, 1982)pp. 1528


• 46. Tsang, W.S.;Clarke, M.A.; Parrish, F.W. "Determination of Aspartameand Its Breakdown Products in Soft Drinks by Reverse-Phase Chromatographywith UV Detection." Journal of Agricultural Fd. Chemicals 33:734-738 (l985)


• 47. Davoli, E.; Cappeilini, L.' et al. "Serum Methanol Concentrations inRats and in Men after a Single Dose of Aspartame." Fed. ChemicalToxicology 24 (3):187-189 (l986).


• 48. Uribe, M. "Potential Toxicity of a New Sugar Substitute in Patientswith Liver Disease." New England Journal of Medicine. 306 (3):173-174(Jan 21, 1981).


• 49. Wurtman, R.J. "Neurochemical Changes Following High Dose Aspartamewith Dietary Carbohydrates." New England Journal of Medicine 309:7(August 18, 1982).


• 50. Sharma, R.P.; Coulombe, R.A., Jr. "Effects of Repeated Doses ofAspartame on Serotonin and its Metabolite in Various Regions of the MouseBrain." Toxicology Program, Department of Animal, Dairy and VeterinarySciences. Utah State University. (l986).


• 51. Young, S.N.: Smith, S.E.; et al. "Tryptophan Depletion Causes aRapid Lowering of Mood in Normal Males." Psychopharmocology. 87: 173-177(l985).


• 52. Padridge, W.M. "The Safety of Aspartame." J of the American MedicalAssociation 256 (19):2678. (November 21, l986).


• 53. Roberts, H.J. "New Perspectives Concerning Alzheimer's Disease." OnCall (August 1989) pp. 14-16


• 54. Walton, R.G.: Hudak, R.: and Green-Waite, R.J. "Adverse REactions toAspartame: Double-blind Challenge in Patients from a VulnerablePopulation." Biological Psychiatary pp. 13-17 (l993).


• 55. Lipton, S.A.: Rosenberg, P.A. "Excitatory Amino Acids as a Finalcommon Pathway for Neurologic Disorders." New England Journal ofMedicine 330 (9):613-622 (l994).


• 56. Dow-Edwards, D." Scribani, L.: and Riley, E.P. "Impaired Performanceon Odor-Aversion Testing Follow Prenatal Aspartame Exposure in the GuineaPig." Neurotoxicology and Teratoiogy 11:413-416 (l989).


• 57. Millstone, E. "Sweet and Sour: The Unanswered Questions aboutAspartame." The Scoiogist Volume 24, Number 2 (March/April 1994).