Wetenschappelijk onderzoek materiaal over de zoetstof aspartaam!

Door onafhankelijke onderzoekers

Vertaling: Ed Gunneweg

  • 1. Stegink, L.: Filer, L.J. Jr. Aspartame Physiology and Biochemistry.University of Iowa College of Medicine. Iowa City, IA Marcel Dekker,Inc. 1984.

  • 2. Camfield, P.R.: Camfield, J.M.: Dooley, J.M.: et al with generalizedabsence epilepsy: A double-blind controlled study. Neurology (42) 1000-1003(May 1992)

  • 3. Boehm, M.: Bada, J. Racemization of aspartic acid and phenylalaninein the sweetener aspartame at 100 degrees C. Proc. Natl. Acad. Sci. USA(81) August 1984.

  • 4. Walton, R. G. "Seizure and mania after high intake of aspartame."Psychopathology 17:98-106 (1984)

  • 5. Drake, M.E. "Panic Attacks and Excessive Aspartame Ingestion." TheLancet (Sept 13, l986) p. 631

  • 6. Walton, R. G. "The Possible Role of Aspartame in Seizure Induction"Proceedings of the First International Meeting on Dietary Phenylalanineand Brain Function. (May 8-10 1987) pp.495-499

  • 7. Epstein, C. M.: Trotter, J.F.: et al "EEG Mean Frequencies areSensitive indices of Phenylalanine Effects on Normal Brain."Electroencephalography and Clinical Neurophysiology 72:133-139 (1989)

  • 8. Pinto, J.M.B." Maher, T. J. "Administration of Aspartame PotentiatesPentlyeneterazole and Fluorothyl-Induced Seizure in Mice."Neuropharmacology 27 (1):51-55 (l988)

  • 9. Olney, John "Excitatory Neurotoxins as Food Additives: An Evaluationof Risk." Neurotoxicology 2:163-192 (1980)

  • 10. Koehler S.M.: Glaros, A. "The effect of aspartame on migraineheadache." Headache 28:000-000 (l988)

  • 11. Edmeada, J. Editorial: "Aspartame and Headache." Headache, pp.64-65(February, 1988)

  • 12. Lipton, R. B.; Newman, L. C.: Solomon, S. "Aspartame and headache,(re:Schiffman et al study)," New England Journal of Medicine 318 (18):1200-1201 (May 5, 1988)

  • 13. Steinmetzer, R.V.: Kunkel, R.S. "Aspartame and Headache" New EnglandJournal of Medicine 318 (18): 1201 (May 5, 1988)

  • 14. Koehler, Shirley; and Glaros, Alan. "The Effect of Aspartame onMigraine Headache." Headache 28 (1):10-14 (l988)

  • 15. Olney, J. W.; and Ho, Ol. "Brain damage in Infant Mice FollowingOral Intake of Glutamate, Aspartate or Cysteine." Nature 227:609-611(August 8, 1970)

  • 16. Olney, J. W. "Excitotoxic Food Additives - Relevance of AnimalStudies to Human Safety." Neurological Behavioral Toxicology andTeratology 6:455-462 (l984).

  • 17. Olney, J. W.; Labruyere, J: DeGubaret, T. "Brain Damage in Mice fromVoluntary Ingestion of Glutamate and Aspartame." NeurobehavioralToxicology 2:125-129 (l980)

  • 18. Roberts, H. J. "Does Aspartame Cause Human Brain cancer?" Journal ofAdvances in Medicine 4 (4): 231-241 (Winter, 1991).

  • 19. Potenza, D." El-Mailakh, Rif S. "Aspartame: Clinical Update."Connecticut Medical Journal 53 (7): 395-400 (l989)

  • 20. Sardesai, V.M.: Holliday, J.F.; et al. "Effect of Aspartame in Normaland Diabetic Rats." Biochemical Archives 2:237-243 (l986)

  • 21. Federal Register 48:54993-54995 (Dec 8, l983)

  • 22. Yokigoshi, H.: Roberts, C. F&t;: Caballero, B.: Wurtman, R. J."Effects of Aspartame and Glucose Administration on Brain and PlasmaLevels of Large Neutral Amino Acids and Brain 5-Hydroxyindoles." AmericanJournal of Clinical Nutrition. 40:1-7 (July 1, 1984)

  • 23. Krause, W.:Halminksi, M." et al. "Biochemical and NeuropsychologicalEffects of Elevated Plasma Phenylalanine in Patients with TreatedPhenylketonuria." Journal of Clinical Investigation 75: 40-48 (January,1985).

  • 24. Pardridge, W.M. "Potential Effects of the Dipeptide SweetenerAspartame on the Brain. Nutrition and the Brain 7:199-241 (l986)

  • 25. Gaines, S. M.: Bada, J.I. "Reversed Phase, High-Performance LiquidChromatographic Separation of Aspartame Diastereomeric DecompositionProducts." Journal of Chromatography. 389-:219-225 (l987)

  • 26. Filer, L. J.; Stegnink. L.D. "Effect of Aspartame on PlasmaPhenylalanine Concentration in Humans." Proceedings of the FirstInternational Meeting on Dietary Phenylalanine and the Brain Function(May 8-10, l987) pp 25-26

  • 27. Matalon, R.: Michals, K.:et al. "Aspartame Consumption in NormalIndividuals and Carriers for Phenylketonuria (PKU)." Proceedings of theFirst International Meeting on Dietary Phenylalanine and Brain Function(May 8-10, l987) pp. 81-93

  • 28. Matalon, R. Michals, K." Sullivan, D.; et al. "Aspartame Consumptionin Normal Individuals and Carriers for Phenylketonuria (PKU)." Universityof Illinois at Chicago, Department of Pediatrics, Nutrition and MedicalDietetics and Epidemiology and Biometry, Chicago, Illinois (l986).

  • 29. Tocci, P.M.: Beber, B. "Anomalous Phenylalanine Loading Responses inRelation to Cleft Lip and Cleft Palate." Pediatrics 52: 109-113 (July l973)

  • 30. Steilman, S.D.:Garfinkel, L. "Artificial Sweetener and One YearWeight Change Among Women." Preventative Medicine 15:195-202 (l986)

  • 31. Blundell, J.E.: Hill, A.H. "Paradoxical Effects of an IntenseSweetener (Aspartame) on Appetite." The Lancet (May 10, l986) pp. l092-1093.

  • 32. Garriga, M., MD; and Metcalf, D.,MD. "Aspartame intolerance" Annalsof Allergy 61:63-66 (December 1988)

  • 33. United States General Accounting Office/HRD-87-86, Food and DrugAdministration's Approval of Aspartame. (June l987)

  • 34. Council Report: Aspartame review of safety issues. Journal of theAmerican Medical Association l985:254 (3):400

  • 35. Johns,D.R., MD, Letter to the Editor. The New England Journal ofMedicine (August 14, 1986)

  • 36. Novick, N.J. "Aspartame-induced granulomatous panniculitis." Annalsof Internal Medicine 102:206-207 (l985)

  • 37. McCauliffe, D.: and Poitras, K. "Aspartame-induced lobularpanniculitis." J of the American Academy of Dermatology 24 (2):298-299(February 1991)

  • 38. Kulezycki,A.Jr. "Aspartame induced urticaria. Annals of InternalMedicine 104:207-208 (l986)

  • 39. Wurtman, R.J. "Aspartame: possible effect on seizuresusceptibility." Lancet 2:1060. (l985)

  • 40. Schainker, N. and Olney, J.W. "Glutamate Type Hypothalamic PituitarySyndrome in Mice Treated with Aspartame or Cysteate in Infancy." Journalof Neutral Trans. 35: 207-215 (l974)

  • 41. Reynolds, W. A.: Butler, V." Lemley-Johnson, N. "HypothalamicMorphology Following ingestion of Aspartame of MSG in the Neonatal Rodentand Primate: A Preliminary Report" Journal of Toxicology andEnvironmental Health 2:471-480 (l976)

  • 42. Pizzi, W.J.:Tabor, J.M.:Barnhart,J. "Somatic, Behavioral andReproductive Disturbances in Mice Following Neonatal Administration ofSodium L-Aspartate." Pharmacological Biochemical Behavior 9::481-485 (l976)

  • 43. Stegnik, L.D.: Brummel, M.C.; et al, "Blood Methanol Concentrationsin Normal Adult Subjects Administered Abuse dose of Aspartame." J ofToxicological Environmental Health 7:281-290 (l981)

  • 44. Monte, Woodrow, "Aspartame: Methanol and the Public Health," Journalof Applied Nutrition 36(1):42-54 (l984).

  • 45. Bergeron, R.:Cardinal, J." et al. "Prevention of Methanol Toxicityby Ethanol Therapy." New England Journal of Medicine (December 9, 1982)pp. 1528

  • 46. Tsang, W.S.;Clarke, M.A.; Parrish, F.W. "Determination of Aspartameand Its Breakdown Products in Soft Drinks by Reverse-Phase Chromatographywith UV Detection." Journal of Agricultural Fd. Chemicals 33:734-738 (l985)

  • 47. Davoli, E.; Cappeilini, L.' et al. "Serum Methanol Concentrations inRats and in Men after a Single Dose of Aspartame." Fed. ChemicalToxicology 24 (3):187-189 (l986).

  • 48. Uribe, M. "Potential Toxicity of a New Sugar Substitute in Patientswith Liver Disease." New England Journal of Medicine. 306 (3):173-174(Jan 21, 1981).

  • 49. Wurtman, R.J. "Neurochemical Changes Following High Dose Aspartamewith Dietary Carbohydrates." New England Journal of Medicine 309:7(August 18, 1982).

  • 50. Sharma, R.P.; Coulombe, R.A., Jr. "Effects of Repeated Doses ofAspartame on Serotonin and its Metabolite in Various Regions of the MouseBrain." Toxicology Program, Department of Animal, Dairy and VeterinarySciences. Utah State University. (l986).

  • 51. Young, S.N.: Smith, S.E.; et al. "Tryptophan Depletion Causes aRapid Lowering of Mood in Normal Males." Psychopharmocology. 87: 173-177(l985).

  • 52. Padridge, W.M. "The Safety of Aspartame." J of the American MedicalAssociation 256 (19):2678. (November 21, l986).

  • 53. Roberts, H.J. "New Perspectives Concerning Alzheimer's Disease." OnCall (August 1989) pp. 14-16

  • 54. Walton, R.G.: Hudak, R.: and Green-Waite, R.J. "Adverse REactions toAspartame: Double-blind Challenge in Patients from a VulnerablePopulation." Biological Psychiatary pp. 13-17 (l993).

  • 55. Lipton, S.A.: Rosenberg, P.A. "Excitatory Amino Acids as a Finalcommon Pathway for Neurologic Disorders." New England Journal ofMedicine 330 (9):613-622 (l994).

  • 56. Dow-Edwards, D." Scribani, L.: and Riley, E.P. "Impaired Performanceon Odor-Aversion Testing Follow Prenatal Aspartame Exposure in the GuineaPig." Neurotoxicology and Teratoiogy 11:413-416 (l989).

  • 57. Millstone, E. "Sweet and Sour: The Unanswered Questions aboutAspartame." The Scoiogist Volume 24, Number 2 (March/April 1994).

  • Nog enige referenties:

    • Kulczycki Jr., Anthony, 1995, "Aspartame-induced hives," Journal of Allergy & Clinical Immunology, February 1995, page 639-640.

    • Olney, John W., 1994. "Excitotoxins in Foods," NeuroToxicology, Volume 15, Number 3, page 535-544.

    • Roberts, H.J., 1988. "Reactions Attributed to Aspartame- Containing Products: 551 Cases," Journal of Applied Nutrition, Volume 40, page 85-94.

    • Van Den Eeden, SK, et al., 1994. "Aspartame Ingestion and Headaches," Neurology, Volume 44, page 1787-1793.

          Een onderzoek van Dr. Diana Dow-Edwards, werd oorspronkelijk gesubsidieerd door Nutrasweet. Toen bleek dat de uitkomsten rampzalige waren, trokken ze de subsidie in en moest Dr. Dow-Edwards het onderzoek zelf bekostigen. NutraSweet weigerde het onderzoek te aanvaarden.

          In haar boek: "THE TAINTED TRUTH; THE MANIPULATION OF FACT IN AMERICA",(De besmette waarheid; de manipulatie van de waarheid in Amerika) zegt Cinthia Crossen: "De weg naar de hel was geplaveid met de overvloed van de gezamenlijke research Dollars, die in 1991 al boven de $2.1 miljard waren gestegen. Wetenschappers werken dus voor mensen die niet houden van negatieve uitslagen en die verder onderzoek van die onderzoekers zeker niet zullen financieren. .."In de huidige door bedrijven gedomineerde informatiemarkt, behoort de waarheid aan hen die de opdracht er voor geven."

          U kunt nu besluiten of u een zoetstof wilt gebruiken die in werkelijkheid een dodelijk drug is die epileptische grand-mall insulten, hersentumoren en andere soorten kanker, (92 door de FDA gedocumenteerde symptomen en invaliditeit) heeft veroorzaakt en dodelijk kan zijn voor diabetes patiĆ«nten!

    • Een link naar de wetenschappelijk onderzoeker, Mark Gold's aspartaam website.

    • De website van Dave Rietz (helaas veel te jong overleden door de gevolgen van aspartaam) met meer dan 200 pagina's met meer dan 4 MB tekst... http://www.dorway.com

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